Omk1®
Rationale
Glaucoma, according to the current definition by European Glaucoma Society, is a chronic, progressive, potentially blinding, irreversibile eye disease causing optic nerve rim and Retinal Nerve Fiber Layer (RNFL) loss with related visual field defects. Up to date glaucoma is the second cause of blindness in developing countries. It is now established that Glaucoma is a Neurodegenerative disease and how the complex connection between the eye and the brain is an important key to the disease. Although the main risk factor is high intraocular pressure, international Literature showed that in a high percentage of patients (45%), despite an apparently well-controlled IOP, the damage to nerve fibers and, consequently, to the visual field continue to progress. The evidence that glaucoma is a neurodegenerative disease and the percentage of patients who worsen despite a well-controlled IOP, have been oriented International Scientific research to explore and study neuroprotective molecules to be added to hypotensive therapy, which were able to protect, delay or reduce the RGC loss by acting on cells undergoing apoptosis.
Among the neuroprotectors, the widely studied in glaucoma disease is Citicoline, molecule with a double mechanism of action: structural (by restoring membranes phospholipids) and functional. About the use of citicoline on glaucoma, there is a growing clinical evidence of its efficacy (in intramuscular, oral solution and eye drops administration) as neuroprotective treatment in addition to hypotensive therapy.
Omk1®has been developed to acts where the damage begins on Retinal Ganglion Cells and Optic Nerve head.
What Omk1®is
OMK1® is a sterile ophthalmic solution in a 10 ml bottle containing 2% of Citicoline and 0,2% of high molecular weight Hyaluronic acid.
When to use Omk1®
Thanks to the presence of Citicoline and to its structural action on retinal ganglion cells, OMK1® is indicated in Glaucomatous patients as coadjuvant to hypotensive therapy. Moreover, the wetting and protective properties of the product ensure ocular relief in case of irritation, burning and foreign body sensation caused by environmental factors, eye surgery or conjunctivitis.
How much and how to use Omk1®
1 drop 3 times per day